PKU sphere® liquid

A ready-to-drink, low-phenylalanine (low-Phe) formula for use in Phenylketonuria (PKU) diet management for adults, children, and teens

Glycomacropeptide-based (GMP-based) PKU formula designed for great taste and to support management of blood Phe levels

Low in added sugars - just 4.3 g per serving

Low volume per gram of protein equivalent

PKU sphere liquid is suitable from 3 years of age
FOR USE UNDER MEDICAL SUPERVISION.

View full product information

FLAVORS

Vanilla

Banana - NEW!

Chocolate - NEW!

Request Sample

FLAVORS

Vanilla

Banana - NEW!

Chocolate - NEW!

A ready-to-drink, low-phenylalanine (low-Phe) formula for use in Phenylketonuria (PKU) diet management for adults, children, and teens

Glycomacropeptide-based (GMP-based) PKU formula designed for great taste and to support management of blood Phe levels

Low in added sugars - just 4.3 g per serving

Low volume per gram of protein equivalent

PKU sphere liquid is suitable from 3 years of age
FOR USE UNDER MEDICAL SUPERVISION.

View full product information

Request Sample

Features

Unique 60:40 GMP:Amino Acid blend designed to taste great & maintain blood Phe in target range.
- 60% GMP derived from a natural protein source.¹ This bioactive peptide with prebiotic properties may support gut health.^1-2
- 40% Amino Acid with the amino acid profile that has been critically evaluated and tailored to support better management of blood Phe levels.^3-4
Low in added sugars, with only 4.3 g per serving. That's about one teaspoon of sugar per bottle
20 g protein equivalent (PE) in just one 8 fl oz bottle, to help with achieving daily intake goals with less volume and fewer servings.
Great tasting with two new flavors.
Wide range of vitamins, mineral and DHA to support adequate intake of nutrients lacking in the typical PKU diet.^5-9

PKU sphere liquid contains the same carefully designed and clinically evaluated GMP:Amino Acid blend as PKU sphere powder.

References:

1. Rackerby et al. Food Sci Anim Resour, 2024.

2. Sawin et al. Am J Physiol GI, 2015

3. . Daly A et al., J Hum Nutr Diet, 2017.

4. Daly A et al., Orphanet J Rare Dis, 2019.

5. Couce ML, et al. Effects of LC-PUFA Supplementation in Patients with Phenylketonuria: A Systematic Review of Controlled Trials. Nutrients. 2019; 11(7):1537.

6. Reilly C, et al. Trace element nutrition status and dietary intake of children with phenylketonuria. Am J Clin Nutr. 1990; 52(1):159–165.

7. Barretto JR, et al. Poor zinc and selenium status in phenylketonuric children and adolescents in Brazil. Nutr Res. 2008; 28(3):208–211.

8. Gokmen-Ozel HA, et al. Long-term efficacy of ‘ready-to-drink’ protein substitute in phenylketonuria. J Hum Nutr Diet. 2009; 22(5):422–427.

9. Knerr I, Blessing H. Seyferth S, Watling RJ, and Chaudhri MA. Evaluation of plasma trace element and mineral status in children and adolescents with phenylketonuria using data from inductively-coupled-plasma atomic emission and mass spectrometric analysis. Ann Nutr Metab. 2013; 63(1-2):168–173.

Nutrition Information

per 237 ml (1 carton, vanilla)

120
Calories
20 g
Protein Equivalent
6.6 g
Carbohydrate
1.2 g
Total Fat
109 mg
DHA

Ordering & Reimbursement Information

Product	Packaging	Product Number	Reimbursement Code	HCPCS Code
PKU sphere liquid Banana	15 x 8 fl oz bottles (15 x 237 ml)	26112	12539-0026-11	B4162 & B4157
PKU sphere liquid Chocolate	15 x 8 fl oz bottles (15 x 237 ml)	26105	12539-0026-10	B4162 & B4157
PKU sphere liquid Vanilla	15 x 8 fl oz carton (15 x 237 ml)	25849	12539-0025-84	B4162 & B4157