- Contains glycomacropeptide (GMP) from a natural whole protein source: offering a different taste to amino acid based medical foods which may be preferred by some individuals with PKU1-4
- 20 g protein equivalent (PE) in ONLY one 8 fl oz carton to help achieve daily intake of PE in the lowest volume**
- Convenient and resealable carton: easy to take on-the-go to daycare, school, work, or when traveling
- PKU sphere20 liquid is now available in a Tetra Pak® reducing the amount of virgin plastic by 76%^
- Wide range of vitamins, minerals and DHA to support adequate intake of nutrients lacking in the typical PKU diet5-9
- Can be taken as is or easily customized with permitted flavorings
* Each 8 fl oz carton contains 30 mg of phe
** Among ready-to-drink GMP-based medical foods for PKU.
^when comparing each individual plastic bottle to an individual Tetra Pak
|26.85 g plastic
||6.57 g plastic
1. Lim K, et al. Acceptable low-phenylalanine foods and beverages can be made with glycomacropeptide from cheeses whey for individuals with PKU. Mol Gen Metab. 2007; 31:92(1):176–8.
2. Van Calcar SC, et al. Improved nutritional management of Phenylketonuria by using a diet containing glycomacropeptide compared with amino-acids. Am J Clin Nutr. 2009; 89(4):1068–77.
3. Ney, D. Glycomacropeptide for nutritional management of phenylketonuria: a randomized, controlled, crossover trial. Am J Clin Nutr. 2016; 104(2):334–45.
4. Proserpio C, et al. Exploring Drivers of Liking of Low-Phenylalanine Products in Subjects with Phenylketonuria Using Check-All-That-Apply Method. Nutrients. 2018; 10(9):1179.
5. Couce ML, et al. Effects of LC-PUFA Supplementation in Patients with Phenylketonuria: A Systematic Review of Controlled Trials. Nutrients. 2019; 11(7):1537.
6. Reilly C, et al. Trace element nutrition status and dietary intake of children with phenylketonuria. Am J Clin Nutr. 1990; 52(1):159–165.
7. Barretto JR, et al. Poor zinc and selenium status in phenylketonuric children and adolescents in Brazil. Nutr Res. 2008; 28(3):208–211.
8. Gokmen-Ozel HA, et al. Long-term efficacy of ‘ready-to-drink’ protein substitute in phenylketonuria. J Hum Nutr Diet. 2009; 22(5):422–427.
9. Knerr I, Blessing H. Seyferth S, Watling RJ, and Chaudhri MA. Evaluation of plasma trace element and mineral status in children and adolescents with phenylketonuria using data from inductively-coupled-plasma atomic emission and mass spectrometric analysis. Ann Nutr Metab. 2013; 63(1-2):168–173.